If driving north from the Moscow/Lewiston/Clarkston area, take Highway 66 to Palouse.
If driving south from the Couer D Alene area, go past take the new super smooth Highway 6 / WASR 272 to Palouse.
If coming from Spokane take either Highway 27 (South on Pines) and enjoy, or hustle on down on Highway 195 and turn at the WSU alt route after Rosalia.
If coming in from the West come in on Highway 272 from Colfax and take a right on Main Street.